Obsessive-Compulsive Disorder (OCD) is a chronic and long-lasting disorder in which aperson has uncontrollable, recurrent thoughts (obsessions) andbehaviours (compulsions) that he or she feels the urge to repeat overand over1.Pharmacological andpsychotherapeutic measures are the twomost widely used approaches2.
Clomipramine was the first agent found to have efficacy in OCD .The drug has the pharmacological properties of thetricyclic group of antidepressants 3.The antidepressant effectsof clomipramine are believed to be due to reuptake inhibition of serotonin and norepinephrine while serotonin reuptake inhibition onlyis believed to be cause for the efficacy of clomipramine in the treatment ofOCD4. SSRIs are the first line drugs in treating OCD. The adverse reactions ofSSRIs are less, so improved compliance is observed.
Available SSRIsinclude fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil),citalopram (Celexa), escitalopram (Lexapro), and sertraline (Zoloft)5.Despite the provenefficacy of SSRIs and clomipramine in OCD, many patients show no or just partial symptom improvement to a medication.The combination of the antipsychotics risperidone, haloperidol, olanzapine, orquetiapine along with an SSRI was foundto be to be more efficacious than SSRI therapy in such cases and is suggestedby the WFSBP WorldFederation of Societies of Biological Psychiatry6.Prescribing a suitablemedication for a particular patient is done on the basis of many factorsincluding patient’s demographic characteristics, illness history, side effectsof the medication, co morbidities. So, a study of prescription patternscan help in identifying prevalent practices of the use of medications.7.The concept of QOL is often considered a missingmeasurement in healthcare. Knowledge about QOL was found to be useful because many studies showedcorrelations between QOL and distress that often leads to worsening of symptoms such as those of OCD.
Hence, the aimof the present study was to assess QOL in patientssuffering from OCD8.Today, in an age where health care is scrutinized, notonly for the quality of that which we provide but also the satisfaction ofthose who receive it. So, it isnecessary to find out weaknesses insystems to aid improvement through the patient’s eyes9.