Obsessive-Compulsive found to have efficacy in OCD .The drug

Obsessive-Compulsive Disorder (OCD) is a  chronic and long-lasting disorder in which a
person has uncontrollable, recurrent thoughts (obsessions) and
behaviours (compulsions) that he or she feels the urge to repeat over
and over1.

Pharmacological and
psychotherapeutic  measures are the two
most widely used approaches2.

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Clomipramine was the first  agent found to have efficacy in OCD .The drug has the pharmacological properties of the
tricyclic group of antidepressants  3.The antidepressant effects
of clomipramine are believed to be due to reuptake inhibition of serotonin and norepinephrine
 while serotonin reuptake inhibition only
is believed to be cause for the efficacy of clomipramine in the treatment of

SSRIs are the first line drugs  in treating OCD. The adverse reactions of
SSRIs are less, so improved compliance is observed.  Available SSRIs
include fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil),
citalopram (Celexa), escitalopram (Lexapro), and sertraline (Zoloft)5.

Despite the proven
efficacy of SSRIs and clomipramine in OCD, 
many patients show no or just partial symptom improvement to a medication.
The combination of the antipsychotics risperidone, haloperidol, olanzapine, or
quetiapine along  with an SSRI was found
to be to be more efficacious than SSRI therapy in such cases and is suggested
by the WFSBP World
Federation of Societies of Biological Psychiatry6.

Prescribing a suitable
medication for a particular patient is done on the basis of many factors
including patient’s demographic characteristics, illness history, side effects
of the medication, co morbidities. So, a study of prescription patterns
can help in identifying prevalent practices of the use of medications.7.

The concept of QOL is often considered a missing
measurement in healthcare. Knowledge  about QOL was found  to be useful because many studies showed
correlations between QOL and distress that often leads to worsening of  symptoms such as those of OCD. Hence, the aim
of the present study was to assess  QOL   in patients
suffering from OCD8.

Today, in  an age where health care is scrutinized, not
only for the quality of that which we provide but also the satisfaction of
those who receive it.  So, it is
necessary to find out  weaknesses in
systems to aid improvement through the patient’s eyes9.


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