Dear Sir or Madam,Whata great honor to have a contact with you! Let me take this opportunity tointroduce myself, my name is Eman Mohamed Abdelrazik, a fresh biotechnologygraduate. The main core of my four-year bachelor study is molecular biology andgenetic engineering. I have a special interest in cancer biology and genomicanalysis. Nowadays, I have enrolled in Genomic Data Science Specialization thatis offered by Johns Hopkins University at Coursera’s platform. My interest incancer biology encouraged me to start my graduation research project entitled, TheEffect of some Natural Anticancer Agents on Autophagy and ExtracellularRegulated Protein Kinase Pathway in Hepatocellular Carcinoma Cell.
For aneight-month period, I worked hardly from choosing the idea with the help of mysupervisors to designing the methodology, choosing candidate genes, performingpractical work, troubleshooting and writing research thesis. The idea behind myproject was to choose a natural anticancer agent that can induceautophagy-mediated cell death and prevent resistance to chemotherapy throughmodulation of autophagy. I tested the anticancer effect of three compounds butonly Carnosic Acid and Glycyrrhetinic Acid gave excellent result throughinhibition of ERK pathway and induction of apoptosis and autophagy. Thesefindings have indicated their potential role as candidates for cancer therapyand maybe an alternative to Sorafenib. Aftergraduation, I have decided to complete my research on a large scale of genes. Ihave been lucky to find the Life Sciences Summer Research Program (SRP) at theEcole Polytechnique Fédérale de Lausanne (EPFL).
What encourages me to apply isthat I find EPFL ranking is the 12th in the world according to QS -World University ranking and the 3rd in Europe according to Leidenranking , which place EPFL within the world’s best schools in the fields ofbasic sciences, especially life sciences. I also have read the feedback frompast SRP participants who came from giant Universities such as, Harvard,Oxford, Washington, Georgia, Heidelberg and Cornell. Their positive feedbackgive me the greatest encouragement to keep pursuing my passionfor cancer biology research. I know that I will get more than enough experiencein my laboratory work through the perfect program of SRP that combine valuableaspects such as, the hands-on experience and training at highly specialized,well-equipped labs under the supervision of lab head. It will also covertheoretical and practical part through series of weekly workshops and seminars.The value of SRP program reaches to its peak by poster session which allow meto represent my research work to my peers and my teachers. The representationand criticism will give me insights into strong and weak points in my researchand even new research ideas. Finally, SRP will be my first internationalexperience.
Tosum up, SRP will provide the three sides of educational triangle; the rightplace with the right peers and teachers at the perfect time. As an agent inthis perfect community, I will share my knowledge with my peers. We will learnfrom, teach, encourage, provide constructive feedback to, and inspire eachother. I will make sure that my research will be one of the top ten at SRP,which will add a great value to the program. I think the main purpose of ourengagement is to celebrate the wealth of diverse.
Thankyou in advance. I am looking forward to your response. Best regards,Eman Abdelrazik