CAR T- CELL THERAPHY:Definition:Car-T cell is the type of treatment in which a patient’s T cells which are besically a type of immune system cells that are changed in the labo, so they will often attack cancer cells. While The T cells are observe from a patient’s blood. Then the gene for a special receptor that attach to a specific protein on the patient’s cancer cells is added in the lab. Here The special receptor is known then a chimeric antigen receptor which is also known as CAR. One thing about CAR T cells that known numbers of the CAR T cells are grown in the laboratory and given to the patient by infusion.
CAR T-cell therapy is being studied in the treatment of some types of cancer. It is Also said to be chimeric antigen receptor T-cell therapy. How Car T Theraphy Works:The immune system defence our body against the disease wheres T cells target that defective cell and abnormal cells. Now Scientist genetically engineered patient own T cells to make them Smarter and stronger for destroying cancerOne version is Called Car t cell Theraphy . While The T cell customize the zero vein on patient specific kind of cancer . but it will start to the situation when the patient blood filter to a machine separate T cells and other white blood cells from the rest of all. Scientist mix the All Collective T cells with the Virus that has been disable. Instead that Virus carries genetic instruction for the T cells to grow in order artificial receptors called them Chimeric Antigen Receptor also called CAR.
Which will tracking cancer target While Million of Car T cells grows in the laboratory and give back to the patient interveniously. The first called t cell are being tested against type of Leukemia and lymphoma they bear a marker or antigen named as cd19 Antigen. Once in the blood stream those Car T cell those Chemric Antigen are Grab hold, they will release toxic chemicals that trigger a cancers cell die. So As One Cancers Cell die involved to the next, multiplying into the patient blood and no need longer.ADVANTAGES: Advantages of CAR- T cells theraphy are discussed as bellow:1. MHC independent.
2. Overcome MHC molecule down regulation.3. Production of large no of tumor specific cells in a moderately short period of time.